作者单位:Department of Newborn and Developmental Paediatrics, Sunnybrook Health Sciences Centre, Sunnybrook[1]Program in Child Health Evaluative Sciences, SickKids Research Institute, Dalla Lana School of[2]MedImmune, One MedImmune Way, Gaithersburg, MD 20878, United States[3]Department of Physiology, Fraser Mustard Institute of Human Development, University of Toronto[4]