Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-beta-D-ribose 2 '-Oxidase

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作者： Oh, Sangmi ^[1] ; Park, Yumi ^[2] ; Engelhart, Curtis A. ^[3] ; Wallach, Joshua B. ^[2] ; Schnappinger, Dirk ^[1] ; Arora, Kriti ^[1] ; Manikkam, Michelle ^[3] ; Gac, Brian ^[1] ; Wang, Hongwu ^[1] ; Murgolo, Nicholas ^[1] ; Olsen, David B. ^[1] ; Goodwin, Michael ^[1] ; Sutphin, Michelle ^[1] ; Weiner, Danielle M. ^[1] ; Via, Laura E. ^[1] ; Boshoff, Helena I. M. ^[3] ; Barry, Clifton E., III ^[2]

作者单位： NIAID, TB Res Sect, Lab Clin Immunol & Microbiol, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA ^[1] Weill Cornell Med Coll, Dept Microbiol & Immunol, New York, NY 10021 USA ^[2] Merck & Co Inc, Discovery Res, 770 Sumneytown Pike, West Point, PA 19486 USA ^[3]

发布时间 2019-05-23

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Journal of Medicinal Chemistry

2018年61卷22期

9952-9965页

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Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-beta-D-ribose 2 '-Oxidase

Journal of Medicinal Chemistry

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Journal of Medicinal Chemistry

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Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-beta-D-ribose 2 '-Oxidase

Journal of Medicinal Chemistry

相似文献

Journal of Medicinal Chemistry

相关期刊

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