Histone deacetylase inhibitor induction of P-glycoprotein transcription requires both histone deacetylase 1 dissociation and recruitment of CAAT/enhancer binding protein beta and pCAF to the promoter region.
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关键词
1-Phosphatidylinositol 3-KinaseBase SequenceCCAAT-Enhancer-Binding Protein-betaCell LineTumorChromatin ImmunoprecipitationChromonesEnzyme InhibitorsHela CellsHistone DeacetylasesHumansImmunoblottingMorpholinesP-GlycoproteinPeptidesCyclicPromoter RegionsGeneticProtein BindingRNASmall InterferingReverse Transcriptase Polymerase Chain ReactionSignal TransductionSp1 Transcription FactorTranscriptionTransfectionp300-CBP Transcription Factors*1-磷脂酰肌醇3-激酶碱基序列色酮类酶抑制剂HeLa细胞免疫印迹法吗啉类P-糖蛋白肽类环蛋白质结合逆转录聚合酶链反应信号传递转录遗传转染
发布时间
2013-11-20
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Molecular cancer research
735-744页
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