Design and synthesis of conformationally restricted capsaicin analogues based in the 1, 3, 4-thiadiazoleheterocycle reveal a novel family of transient receptor potential vanilloid 1 (TRPV1) antagonists

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作者： Rebolledo,C.L. ^[1] ; Sotelo-Hitschfeld,P. ^[2] ; Brauchi,S. ; Olavarría,M.Z.

作者单位： Institute of Physiology, Faculty of Medicine, University Austral of Chile, Valdivia 5090000, Chile ^[1] Department of Organic Chemistry, Faculty of Chemical Sciences, University of Concepcion, Edmundo ^[2]

关键词 1 3 4-thiadiazole Antagonist activity Capsaicin analogues Restriction conformational TRPV1 receptor

发布时间 2013-11-20

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European Journal of Medicinal Chemistry

2013年66卷

193-203页

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Design and synthesis of conformationally restricted capsaicin analogues based in the 1, 3, 4-thiadiazoleheterocycle reveal a novel family of transient receptor potential vanilloid 1 (TRPV1) antagonists

European Journal of Medicinal Chemistry

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European Journal of Medicinal Chemistry

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Design and synthesis of conformationally restricted capsaicin analogues based in the 1, 3, 4-thiadiazoleheterocycle reveal a novel family of transient receptor potential vanilloid 1 (TRPV1) antagonists

European Journal of Medicinal Chemistry

相似文献

European Journal of Medicinal Chemistry

相关期刊

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