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A Large-Scale Genetic Analysis Reveals a Strong Contribution of the HLA Class II Region to Giant Cell Arteritis Susceptibility

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作者: David Carmona, F. [1] ; Mackie, Sarah L. [2] ; Martin, Jose-Ezequiel [3] ; Taylor, John C. [4] ; Vaglio, Augusto [5] ; Eyre, Stephen [6] ; Bossini-Castillo, Lara [7] ; Castaneda, Santos [8] ; Cid, Maria C. [9] ; Hernandez-Rodriguez, Jose [10] ; Prieto-Gonzalez, Sergio [11] ; Solans, Roser [12] ; Ramentol-Sintas, Marc [13] ; Francisca Gonzalez-Escribano, M. [14] ; Ortiz-Fernandez, Lourdes [15] ; Morado, Inmaculada C. [16] ; Narvaez, Javier [17] ; Miranda-Filloy, Jose A. [18] ; Beretta, Lorenzo [19] ; Lunardi, Claudio [20] ; Cimmino, Marco A. [21] ; Gianfreda, Davide [22] ; Santilli, Daniele [23] ; Ramirez, Giuseppe A. [24] ; Soriano, Alessandra [25] ; Muratore, Francesco [26] ; Pazzola, Giulia [27] ; Addimanda, Olga [28] ; Wijmenga, Cisca [29] ; Witte, Torsten [30] ; Schirmer, Jan H. [31] ; Moosig, Frank [32] ; Schoenau, Verena [33] ; Franke, Andre [34] ; Palm, Oyvind [35] ; Molberg, Oyvind [36] ; Diamantopoulos, Andreas P. [37] ; Carette, Simon [38] ; Cuthbertson, David [39] ; Forbess, Lindsy J. [40] ; Hoffman, Gary S. [41] ; Khalidi, Nader A. [42] ; Koening, Curry L. [43] ; Langford, Carol A. [44] ; McAlear, Carol A. [45] ; Moreland, Larry [46] ; Monach, Paul A. [47] ; Pagnoux, Christian [48] ; Seo, Philip [49] ; Spiera, Robert [50] ; Sreih, Antoine G. [51] ; Warrington, Kenneth J. [52] ; Ytterberg, Steven R. ; Gregersen, Peter K. ; Pease, Colin T. ; Gough, Andrew ; Green, Michael ; Hordon, Lesley ; Jarrett, Stephen ; Watts, Richard ; Levy, Sarah ; Patel, Yusuf ; Kamath, Sanjeet ; Dasgupta, Bhaskar ; Worthington, Jane ; Koeleman, Bobby P. C. ; de Bakker, Paul I. W. ; Barrett, Jennifer H. ; Salvarani, Carlo ; Merkel, Peter A. ; Gonzalez-Gay, Miguel A. ; Morgan, Ann W. ; Martin, Javier
作者单位: Oslo Univ Hosp, Dept Rheumatol, N-0424 Oslo, Norway [1] Ipswich Hosp NHS Trust, Dept Rheumatol, Ipswich IP4 5PD, Suffolk, England [2] Hosp Univ Bellvitge IDIBELL, Dept Rheumatol, Barcelona 08907, Spain [3] Boston Univ, Sch Med, Rheumatol Sect, Boston, MA 02118 USA [4] Univ Penn, Div Rheumatol, Penn Vasculitis Ctr, Philadelphia, PA 19104 USA [5] Univ Leeds, Leeds Inst Rheumat & Musculoskeletal Med, Leeds LS7 4SA, W Yorkshire, England [6] Univ Med Ctr Utrecht, Dept Med Genet, Ctr Mol Med, NL-3584 CX Utrecht, Netherlands [7] Mt Sinai Hosp, Div Rheumatol, Toronto, ON M5T 3L9, Canada [8] Manchester Acad Hlth Sci, NIHR Manchester Musculoskeletal Biomed Res Unit, Manchester, Lancs [9] Mid Yorkshire Hosp NHS Trust, Dewsbury & Dist Hosp, Dept Rheumatol, Dewsbury WF13 4HS, England [10] Hosp Special Surg, Dept Rheumatol, New York, NY 10021 USA [11] Univ Pittsburgh, Div Rheumatol & Clin Immunol, Pittsburgh, PA 15261 USA [12] Univ Barcelona, Hosp Clin, Dept Autoimmune Dis, Vasculitis Res Unit,IDIBAPS, E-08036 Barcelona [13] US, CSIC, Hosp Univ Virgen Rocio, Dept Immunol,IBiS, Seville 41013, Spain [14] Univ Parma, Sch Med, Dept Clin & Expt Med, I-43126 Parma, Italy [15] Cedars Sinai Med Ctr, Div Rheumatol, Los Angeles, CA 90048 USA [16] Johns Hopkins Univ, Div Rheumatol, Baltimore, MD 21224 USA [17] Univ Groningen, Univ Med Ctr Groningen, Dept Genet, NL-9700 Groningen, Netherlands [18] Univ Verona, Dept Med, I-37134 Verona, Italy [19] Hull & East Yorkshire NHS Trust, Dept Rheumatol, Kingston Upon Hull HU3 2JZ, N Humberside, England [20] Univ Hosp Parma, Unit Internal Med & Rheumatol, I-43126 Parma, Italy [21] Fdn IRCCS Ca Granda Osped Maggiore Policlin Milan, Referral Ctr Syst Autoimmune Dis, I-20122 Milan [22] Univ Klinikum Erlangen, Dept Rheumatol & Immunol, D-91054 Erlangen, Germany [23] Croydon Hlth Serv NHS Trust, Dept Rheumatol, Croydon CR7 7YE, England [24] Leeds Teaching Hosp NHS Trust, Dept Rheumatol, Leeds LS7 4SA, W Yorkshire, England [25] Univ Genoa, Dept Internal Med, Div Clin Rheumatol, Res Lab & Acad Div Clin Rheumatol, I-16132 Genoa [26] Univ Utah, Div Rheumatol, Salt Lake City, UT 84132 USA [27] York Teaching Hosp NHS Fdn Trust, Dept Rheumatol, York YO31 8HE, N Yorkshire, England [28] Harrogate & Dist NHS Fdn Trust, Dept Rheumatol, Harrogate HG2 7SX, England [29] North Shore Long Isl Jewish Hlth Syst, Feinstein Inst Med Res, Manhasset, NY 11030 USA [30] Klinikum Bad Bramstedt, Vasculitis Clin, D-24576 Bad Bramstedt, Germany [31] Mayo Clin, Coll Med, Div Rheumatol, Rochester, MN 55905 USA [32] Southend Univ Hosp NHS Fdn Trust, Dept Rheumatol, Westcliff On Sea SS0 0RY, England [33] Univ S Florida, Dept Biostat, Tampa, FL 33612 USA [34] Univ Leeds, Sch Med, Leeds LS9 7TF, W Yorkshire, England [35] Univ Kiel, Inst Clin Mol Biol, D-24105 Kiel, Germany [36] Cleveland Clin Fdn, Ctr Vasculitis Care & Res, Cleveland, OH 44195 USA [37] Univ Hosp Parma, Nephrol Unit, I-43126 Parma, Italy [38] Staffordshire & Stoke On Trent Partnership NHS Tr, Dept Rheumatol, Stoke On Trent ST6 7AG, Staffs [39] McMaster Univ, St Josephs Healthcare, Div Rheumatol, Hamilton, ON L8N 1Y2, Canada [40] Hosp Southern Norway Trust, Dept Rheumatol, N-4604 Kristiansand, Norway [41] Mid Yorkshire Hosp NHS Trust, Pinderfields Hosp, Dept Rheumatol, Wakefield WF1 4DG, England [42] Hosp Clin San Carlos, Dept Rheumatol, Madrid 28040, Spain [43] Hosp Univ Marques de Valdecilla, Dept Rheumatol, IDIVAL, Santander 39008, Spain [44] IRCCS Osped San Raffaele, Unit Internal Med & Immunol, I-20132 Milan, Italy [45] Hosp Xeral Calde, Dept Rheumatol, Lugo 27004, Spain [46] Autonomous Univ Barcelona, Dept Internal Med, Hosp Vall Hebron, Autoimmune Syst Dis Unit, E-08035 [47] Hannover Med Sch, D-30625 Hannover, Germany [48] PTS Granada, CSIC, Inst Parasitol & Biomed Lopez Neyra, Granada 18016, Spain [49] Hosp Princesa, IIS Princesa, Dept Rheumatol, Madrid 28006, Spain [50] Campus Biomedico Univ, Dept Clin Med & Rheumatol, I-00128 Rome, Italy [51] Azienda Osped Arcispedale Santa Maria Nuova, Ist Ricovero & Cura Carattere Sci, Dept Internal Med [52]
发布时间 2015-05-12
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The American Journal of Human Genetics

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