Genetic variation in TLR10 is not associated with chronic Q fever, despite the inhibitory effect of TLR10 on Coxiella burnetii-induced cytokines in vitro

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作者： Ammerdorffer, Anne ^[1] ; Stappers, Mark H. T. ^[2] ; Oosting, Marije ^[3] ; Schoffelen, Teske ^[4] ; Hagenaars, Julia C. J. P. ^[5] ; Bleeker-Rovers, Chantal P. ^[6] ; Wegdam-Blans, Marjolijn C. ; Wever, Peter C. ; Roest, Hendrik-Jan ; van de Vosse, Esther ; Netea, Mihai G. ; Sprong, Tom ; Joosten, Leo A. B.

作者单位： Jeroen Bosch Hosp, Dept Surg, NL-5223 GW Shertogenbosch, Netherlands ^[1] Lab Pathol & Med Microbiol PAMM, Dept Med Microbiol, NL-5504 DL Veldhoven, Netherlands ^[2] Radboud Univ Nijmegen, Med Ctr, Dept Internal Med, NL-6525 GA Nijmegen, Netherlands ^[3] Leiden Univ, Med Ctr, Dept Infect Dis, NL-2333 ZA Leiden, Netherlands ^[4] Cent Vet Inst, Dept Bacteriol & TSEs, NL-8219 PH Lelystad, Netherlands ^[5] Jeroen Bosch Hosp, Dept Med Microbiol & Infect Control, NL-5223 GW Shertogenbosch, Netherlands ^[6]

关键词 Q fever Coxiella burnetii Toll-like receptor 10 Single nucleotide polymorphism Innate immunity

发布时间 2017-04-06

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