Multitarget drug design strategy in Alzheimer's disease: focus on cholinergic transmission and amyloid-beta aggregation

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作者： Simoni, Elena ^[1] ; Bartolini, Manuela ^[2] ; Abu, Izuddin F. ^[3] ; Blockley, Alix ^[4] ; Gotti, Cecilia ^[5] ; Bottegoni, Giovanni ; Caporaso, Roberta ; Bergamini, Christian ; Andrisano, Vincenza ; Cavalli, Andrea ; Mellor, Ian R. ; Minarini, Anna ; Rosini, Michela

作者单位： Univ Nottingham, Sch Life Sci, Univ Pk, Nottingham NG7 2RD, England ^[1] Ist Italiano Tecnol, Drug Discovery & Dev, Via Morego 30, I-16163 Genoa, Italy ^[2] Univ Bologna, Alma Mater Studiorum, Dept Pharm & Biotechnol, Via Belmeloro 6, I-40126 Bologna, Italy ^[3] CNR, Inst Neurosci, Via Luigi Vanvitelli 32, I-20129 Milan, Italy ^[4] Univ Bologna, Alma Mater Studiorum, Dept Life Qual Studies, Corso Augusto 237, I-47921 Rimini, Italy ^[5]

关键词 acetylcholinesterase inhibitors Alzheimer's disease amyloid aggregation multitarget compounds nicotinic receptors

发布时间 2018-02-04

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准确一般字义偏差语意偏离译文作用小提交