Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

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作者： Schulert, Grant S. ^[1] ; Zhang, Mingce ^[2] ; Fall, Ndate ^[3] ; Husami, Ammar ^[4] ; Kissell, Diane ^[5] ; Hanosh, Andrew ; Zhang, Kejian ; Davis, Kristina ; Jentzen, Jeffrey M. ; Napolitano, Lena ; Siddiqui, Javed ; Smith, Lauren B. ; Harms, Paul W. ; Grom, Alexei A. ; Cron, Randy Q.

作者单位： Univ Michigan, Sch Med, Dept Pathol, Ann Arbor, MI USA ^[1] Univ Alabama Birmingham, Childrens Hosp Alabama, Div Pediat Rheumatol, Childrens Pk Pl,Ste 210,1601 ^[2] Cincinnati Childrens Hosp Med Ctr, Div Human Genet, Cincinnati, OH 45229 USA ^[3] Cincinnati Childrens Hosp Med Ctr, Div Pediat Rheumatol, Cincinnati, OH 45229 USA ^[4] Univ Michigan, Sch Med, Dept Surg, Ann Arbor, MI USA ^[5]

关键词 hemophagocytosis macrophage activation syndrome H1N1 influenza perforin cytolytic pathway LYST

发布时间 2017-04-05

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