Isocitrate dehydrogenase 1 and 2 mutations, 2-hydroxyglutarate levels, and response to standard chemotherapy for patients with newly diagnosed acute myeloid leukemia

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作者： Brunner, Andrew M. ^[1] ; Neuberg, Donna S. ^[2] ; Wander, Seth A. ^[3] ; Sadrzadeh, Hossein ^[4] ; Ballen, Karen K. ; Amrein, Philip C. ; Attar, Eyal ; Hobbs, Gabriela S. ; Chen, Yi-Bin ; Perry, Ashley ; Connolly, Christine ; Joseph, Christelle ; Burke, Meghan ; Ramos, Aura ; Galinsky, Ilene ; Yen, Katharine ; Yang, Hua ; Straley, Kimberly ; Agresta, Sam ; Adamia, Sophia ; Borger, Darrell R. ; Iafrate, Anthony ; Graubert, Timothy A. ; Stone, Richard M. ; Fathi, Amir T.

作者单位： Dana Farber Canc Inst, Boston, MA 02115 USA ^[1] Massachusetts Gen Hosp, Boston, MA 02114 USA ^[2] Agios Pharmaceut, Cambridge, MA USA ^[3] Capital Hlth, Trenton, NJ USA ^[4]

关键词 acute myeloid leukemia 2-hydroxyglutarate isocitrate dehydrogenase prognosis remission induction

发布时间 2019-08-16

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