SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3

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作者： Murphy-Benenato, Kerry E. ^[1] ; Dangel, Brian ^[1] ; Davis, Hajnalka E. ^[2] ; Durand-Reville, Thomas F. ^[1] ; Ferguson, Andrew D. ^[3] ; Gao, Ning ^[1] ; Jahic, Haris ^[1] ; Mueller, John P. ^[1] ; Manyak, Erika L. ^[1] ; Quiroga, Olga ^[1] ; Rooney, Michael ^[1] ; Sha, Li ^[1] ; Sylvester, Mark ^[1] ; Wu, Frank ^[1] ; Zambrowski, Mark ^[2] ; Zhao, Shannon X. ^[1]

作者单位： AstraZeneca R&D Boston, Infect Innovat Med, Waltham, MA 02451 USA ^[1] AstraZeneca R&D Boston, Reagents & Assay Dev, Discovery Sci, Waltham, MA 02451 USA ^[2] AstraZeneca R&D Boston, Struct & Biophys, Waltham, MA 02451 USA ^[3]

关键词 Pseudomonas aeruginosa beta-lactam penicillin binding protein siderophore monocarbam structure-guided design

发布时间 2015-10-22

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