Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant
第一作者:
A.M.
作者:
关键词
Cell membranesChlorine compoundsCytologyGene encodingIon exchangeMolecular biologyPlasma stabilityProteinsTemperatureActin cytoskeletonChemical inhibitionCombination therapyHuman bronchial epithelial cellsMacromolecular complexesMembrane stabilityPeripheral proteinsTrans-membrane conductanceCell signalingactincalpain 1ezrinArticlecell membraneCFTR genecontrolled studydown regulationenzyme inhibitiongenegene functiongenetic analysisgenetic variabilityHBEC cell line (bronchial epithelium)humanhuman cellimmunoprecipitationmacromoleculepriority journalproteomics
发布时间
2020-03-21
- 浏览2
The Journal of biological chemistry
13396-13410页
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