Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2-论文-万方医学网

Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2

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作者： Prokopenko, Dmitry ^[1] ; Lee, Sanghun ^[2] ; Hecker, Julian ^[3] ; Mullin, Kristina ^[4] ; Morgan, Sarah ^[5] ; Katsumata, Yuriko ^[6] ; Weiner, Michael W. ^[7] ; Fardo, David W. ; Laird, Nan ; Bertram, Lars ; Hide, Winston ; Lange, Christoph ; Tanzi, Rudolph E. ; Alzheimer's Dis Neuroimaging Initi

作者单位： Harvard University,Massachusetts Gen Hosp ^[1] Grad Sch,Dankook Univ ^[2] Harvard University,Harvard Med Sch ^[3] Dept Biostat,Univ Kentucky ^[4] Dept Radiol & Biomed Imaging,Univ Calif San Francisco ^[5] Dept Biostat,Harvard TH Chan Sch Publ Hlth ^[6] Lubeck Interdisciplinary Platform Genome Analyt,Univ Lubeck ^[7]

关键词 FAMILY-BASED TESTS BETA-DYSTROBREVIN UNIFIED APPROACH PHENOTYPE DATA RISK HAPLOTYPES SCLEROSIS AGE

发布时间 2022-11-01

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