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Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

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第一作者: Craig, Jamie E.
作者单位: Univ Queensland, Inst Mol Biosci, Brisbane, Qld, Australia [1] Moorfields Eye Hosp NHS Fdn Trust, Biomed Res Ctr, Natl Inst Hlth Res, London, England [2] Heidelberg Univ, Med Fac Mannheim, Dept Ophthalmol, Mannheim, Germany [3] Prince Wales Hosp Randwick, Dept Ophthalmol, Sydney, NSW, Australia [4] Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore [5] Royal Adelaide Hosp, South Australian Inst Ophthalmol, Adelaide, SA, Australia [6] Univ Liverpool, Inst Ageing & Chron Dis, Dept Eye & Vis Sci, Liverpool, Merseyside, England [7] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol & Med, Baltimore, MD USA [8] Univ Adelaide, South Australian Inst Ophthalmol, Adelaide, SA, Australia [9] Univ Edinburgh, Med Res Council, Inst Genet & Mol Med, Human Genet Unit, Edinburgh, Midlothian [10] Erasmus MC, Dept Ophthalmol, Rotterdam, Netherlands [11] Kings Coll London, St Thomas Hosp, Dept Ophthalmol, London, England [12] Moorfields Biomed Res Ctr, Natl Inst Hlth Res, London, England [13] Univ Tasmania, Menzies Inst Med Res, Hobart, Tas, Australia [14] Univ Sydney, Westmead Inst Med Res, Ctr Vis Res, Sydney, NSW, Australia [15] Queensland Inst Med Res, Berghofer Med Res Inst, Brisbane, Qld, Australia [16] Auckland Dist Hlth Board, Greenlane Clin Ctr, Eye Dept, Auckland, New Zealand [17] Univ Auckland, Dept Ophthalmol, Auckland, New Zealand [18] Icahn Sch Med Mt Sinai, Dept Ophthalmol, New York, NY USA [19] Harvard Med Sch, Massachusetts Eye & Ear Infirm, Dept Ophthalmol, Boston, MA 02115 USA [20] Flinders Univ S Australia, Flinders Med Ctr, Dept Ophthalmol, Bedford Pk, SA, Australia [21] Macquarie Univ, Fac Med & Hlth Sci, Sydney, NSW, Australia [22] Univ Bern, Univ Hosp Bern, Inselspital, Dept Ophthalmol, Bern, Switzerland [23] Univ Southampton, Fac Med, Clin & Expt Sci, Southampton, Hants, England [24] Case Western Reserve Univ, Sch Med, Dept Populat & Quantitat Hlth Sci, Inst Computat Biol [25] Friedrich Alexander Univ Erlangen Nurnberg, Inst Human Genet, Erlangen, Germany [26] Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands [27] Univ Melbourne, Ctr Eye Res Australia, Melbourne, Vic, Australia [28] Univ Sydney, Sydney Eye Hosp, Fac Med & Hlth, Discipline Ophthalmol, Sydney, NSW, Australia [29] Univ Sydney, Dept Ophthalmol, Sydney, NSW, Australia [30] Ulster Univ, Biomed Sci Res Inst, Coleraine, Londonderry, North Ireland [31]
发布时间 2020-06-02
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Nature Genetics

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