Estimation of a significance threshold for epigenome‐wide association studies

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作者： Saffari Ayden ^[1] ; Silver Matt J. ^[2] ; Zavattari Patrizia ^[3] ; Moi Loredana ^[4] ; Columbano Amedeo ; Meaburn Emma L. ; Dudbridge Frank

作者单位： Department of Biomedical SciencesUniversity of CagliariCagliari,Sardinia,Italy ^[1] Department of Psychological Sciences, BirkbeckUniversity of LondonLondon,United Kingdom ^[2] Department of Non‐Communicable Disease EpidemiologyLondon School of Hygiene and Tropical ^[3] MRC Unit, The Gambia and MRC International Nutrition GroupLondon School of Hygiene and Tropical ^[4]

关键词 CpG DNA methylation epigenetic epidemiology EWAS FWER GWAS permutation resampling simulation extrapolation

发布时间 2018-10-31

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