Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis
作者:
Haberman, Yael [1]
;
Schirmer, Melanie [2]
;
Dexheimer, Phillip J. [3]
;
Karns, Rebekah [4]
;
Braun, Tzipi [5]
;
Kim, Mi-Ok [6]
;
Walters, Thomas D. [7]
;
Baldassano, Robert N. [8]
;
Noe, Joshua D. [9]
;
Rosh, Joel [10]
;
Markowitz, James [8]
;
Crandall, Wallace V. [11]
;
Mack, David R. [12]
;
Griffiths, Anne M. [13]
;
Heyman, Melvin B. [14]
;
Baker, Susan S. [8]
;
Kellermayer, Richard [15]
;
Moulton, Dedrick [16]
;
Patel, Ashish S. [17]
;
Gulati, Ajay S. [18]
;
Steiner, Steven J. [15]
;
LeLeiko, Neal [8]
;
Otley, Anthony [19]
;
Oliva-Hemker, Maria [20]
;
Ziring, David [21]
;
Kirschner, Barbara S. [22]
;
Keljo, David J. [23]
;
Guthery, Stephen L. [24]
;
Cohen, Stanley A. [17]
;
Snapper, Scott [25]
;
Evans, Jonathan [26]
;
Dubinsky, Marla [27]
;
Aronow, Bruce [8]
;
Hyams, Jeffrey S. [15]
;
Kugathasan, Subra [28]
;
Huttenhower, Curtis [8]
;
Xavier, Ramnik J. [29]
;
Denson, Lee A. [30]
作者单位:
Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA
[1]
Childrens Ctr Digest HealthMed, Atlanta, GA USA
[2]
Goryeb Childrens Hosp Atlantic Hlth, Morristown, NJ USA
[3]
Cohen Childrens Med Ctr New York, New York, NY USA
[4]
UT Southwestern Med Ctr Dallas, Dallas, TX USA
[5]
Riley Childrens Hosp, Indianapolis, IN USA
[6]
IWK Hlth Ctr, Halifax, NS, Canada
[7]
Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA
[8]
Med Coll Wisconsin, Milwaukee, WI 53226 USA
[9]
SUNY Buffalo, Buffalo, NY USA
[10]
Univ Chicago, Comer Childrens Hosp, Chicago, IL 60637 USA
[11]
Mt Sinai Hosp, New York, NY 10029 USA
[12]
Sheba Med Ctr, Tel Hashomer, Israel
[13]
Childrens Hosp, 300 Longwood Ave, Boston, MA 02115 USA
[14]
Broad Inst MIT & Harvard, Cambridge, MA 02142 USA
[15]
Nationwide Childrens Hosp, Columbus, OH USA
[16]
Univ Toronto, Hosp Sick Children, Toronto, ON, Canada
[17]
Univ Ottawa, Childrens Hosp Eastern Ontario, Ottawa, ON, Canada
[18]
Nemours Childrens Clin, Jacksonville, FL USA
[19]
Cedars Sinai Med Ctr, Los Angeles, CA 90048 USA
[20]
Univ N Carolina, Chapel Hill, NC 27515 USA
[21]
Texas Childrens Hosp, Baylor Coll, Sch Med, Houston, TX 77030 USA
[22]
Vanderbilt Childrens Hosp, Nashville, TN USA
[23]
Johns Hopkins Univ, Baltimore, MD USA
[24]
Univ Utah, Salt Lake City, UT USA
[25]
UPMC, Childrens Hosp Pittsburgh, Pittsburgh, PA USA
[26]
Connecticut Childrens Med Ctr, Hartford, CT USA
[27]
Emory Univ, Atlanta, GA 30322 USA
[28]
Univ Calif San Francisco, San Francisco, CA 94143 USA
[29]
Hasbro Childrens Hosp, Providence, RI USA
[30]
发布时间
2019-07-16
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Mucosal immunology
Mucosal immunology
491-502页
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