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Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed Physiologically-Based Pharmacokinetic Model of Ritonavir Norvir Tablet Absorption in Humans Under Fasted and Fed State Conditions

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第一作者： Arora, Sumit

作者： Arora, Sumit ^[1] ; Pansari, Amita ; Kilford, Peter ; Jamei, Masoud ; Gardner, Iain ; Turner, David B.

作者单位： Certara UK Ltd, Simcyp Div, Sheffield S1 2BJ, S Yorkshire, England ^[1]

关键词 mechanistic modeling biopharmaceutic IVIV_E oral absorption PBPK model amorphous solid dispersion global sensitivity analysis Simcyp modeling viscosity

发布时间 2021-07-24

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Molecular pharmaceutics

2020年17卷7期

2329-2344页

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Molecular pharmaceutics

2020年17卷7期

2329-2344页

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Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed Physiologically-Based Pharmacokinetic Model of Ritonavir Norvir Tablet Absorption in Humans Under Fasted and Fed State Conditions

Molecular pharmaceutics

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Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed Physiologically-Based Pharmacokinetic Model of Ritonavir Norvir Tablet Absorption in Humans Under Fasted and Fed State Conditions

Molecular pharmaceutics

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Molecular pharmaceutics

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