Disrupting Gram-Negative Bacterial Outer Membrane Biosynthesis through Inhibition of the Lipopolysaccharide Transporter MsbA

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作者： Alexander, Mary Kate ^[1] ; Miu, Anh ^[2] ; Oh, Angela ^[3] ; Reichelt, Mike ^[4] ; Ho, Hoangdung ^[5] ; Chalouni, Cecile ^[6] ; Labadie, Sharada ^[7] ; Wang, Lan ; Liang, Jun ; Nickerson, Nicholas N. ; Hu, Huiyong ; Yu, Lan ; Du, Miaofen ; Yang, Donghong ; Park, Summer ; Kim, Janice ; Xu, Min ; Sellers, Benjamin D. ; Purkey, Hans E. ; Skelton, Nicholas J. ; Koehler, Michael F. T. ; Payandeh, Tian ; Verma, Vishal ; Xu, Yiming ; Koth, Christopher M. ; Nishiyama, Mireille

作者单位： Genentech Inc, Pathol, San Francisco, CA 94080 USA ^[1] Genentech Inc, Struct Biol, San Francisco, CA 94080 USA ^[2] Genentech Inc, Discovery Chem, San Francisco, CA 94080 USA ^[3] Genentech Inc, Biochem & Cellular Pharmacol, San Francisco, CA 94080 USA ^[4] Genentech Inc, Infect Dis, San Francisco, CA 94080 USA ^[5] WuXi AppTec Co Ltd, Shanghai, Peoples R China ^[6] Genentech Inc, Translat Immunol, San Francisco, CA 94080 USA ^[7]

关键词 ABC transporters Enterobacteriaceae Escherichia coli MsbA lipopolysaccharide outer membrane

发布时间 2019-05-22

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