A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity-论文-万方医学网

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A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity

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第一作者： Ding, SL

作者： Ding, SL ^[1] ; Grenier, MC ^[2] ; Tolbert, WD ^[3] ; Vezina, D ^[4] ; Sherburn, R ^[5] ; Richard, J ; Prevost, J ; Chapleau, JP ; Gendron-Lepage, G ; Medjahed, H ; Abrams, C ; Sodroski, J ; Pazgier, M ; Smith, AB ; Finzi, A

作者单位： Ctr Rech CHUM ^[1] Univ Penn ^[2] Uniformed Serv Univ Hlth Sci ^[3] Drexel Univ ^[4] Dana Farber Canc Inst ^[5]

关键词 HIV-1 envelope glycoproteins CD4 mimetics ADCC neutralization Env small-molecule inhibitors HUMAN-IMMUNODEFICIENCY-VIRUS ENVELOPE GLYCOPROTEIN IMMUNOGENS SENSITIZE HIV-1-INFECTED CELLS INNER DOMAIN DENDRITIC CELLS RECEPTOR BINDING ENTRY CORECEPTOR EPITOPES

发布时间 2022-11-06

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A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity

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A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity

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