Selective binding of antimicrobial porphyrins to the heme-receptor IsdH-NEAT3 of Staphylococcus aureus

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作者： Vu,N.T. ^[1] ; Moriwaki,Y. ^[2] ; Caaveiro,J.M.M. ^[3] ; Terada,T. ^[4] ; Tsutsumi,H. ; Hamachi,I. ; Shimizu,K. ; Tsumoto,K.

作者单位： Agricultural Bioinformatics Unit, School of Agricultural and Life Sciences, University of Tokyo ^[1] Department of Biotechnology, University of Tokyo, Tokyo 113-8657, Japan ^[2] Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Kyoto 615-8510, Japan ^[3] Medical Proteomics Laboratory, Institute of Medical Science, University of Tokyo, Tokyo 108-8639 ^[4]

关键词 Antimicrobial compound Isd system Isothermal titration calorimetry Metal recognition Metalloporphyrin Molecular dynamics simulations Protein-heme interaction

发布时间 2013-11-20

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