Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test-论文-万方医学网

Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test

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作者： Harada, Yohei ^[1] ; Sato, Akemi ^[2] ; Araki, Mitsugu ^[3] ; Matsumoto, Shigeyuki ^[4] ; Isaka, Yuta ; Sagae, Yukari ; Abe, Tomonori ; Aoyagi, Yasuko ; Sueoka, Eisaburo ; Okuno, Yasushi ; Kimura, Shinya ; Sueoka-Aragane, Naoko

作者单位： Fac Med,Saga Univ ^[1] Grad Sch Med,Kyoto Univ ^[2] AI Driven Drug Discovery Collaborat Unit,RIKEN Ctr Computat Sci R CCS ^[3] Ctr Innovat Canc Treatment,Tokyo Med & Dent Univ ^[4]

关键词 ERBB2 Variants of unknown significance Extracellular domain Functional analysis Molecular dynamics simulation JOINT-CONSENSUS-RECOMMENDATION EXTRACELLULAR DOMAIN MOLECULAR-DYNAMICS BREAST-CANCER SEQUENCE VARIANTS HER2 MUTATIONS ASSOCIATION INHIBITION ACTIVATION

发布时间 2022-09-16

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Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test

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Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test

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