BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy
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关键词
ABT-737apoptosisautophagyBAXBAK1BCL2BECN1 (Beclin 1)ACTBactinBaf A1bafilomycin A(1)BCL2-antagonistkiller 1BCL2-associated X proteinB-cell CLLlymphoma 2BECN1Beclin 1autophagy-relatedDKOdouble-knockoutFBSfetal bovine serumGAPDHglyceraldehyde-3-phosphate dehydrogenaseHBSSHanks' balanced salt solutionHRPhorseradish peroxidaseMAP1LC3LC3microtubule-associated protein 1 light chain 3MCL1myeloid cell leukemia 1MEFsmouse embryonic fibroblastsMTORmechanistic target of rapamycinPBSphosphate-buffered salineSQSTM1sequestosome 1STSstaurosporineWTwild type
发布时间
2018-12-01
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Autophagy
452-459页
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