Deciphering pharmacogenetic-whole blood/intracellular pharmacokinetic-pharmacodynamic (PG-PK2-PD) relationship of tacrolimus in liver transplant recipients

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作者： Tron, C. ^[1] ; Woillard, J. B. ^[2] ; Houssel-Debry, P. ^[3] ; David, V. ^[4] ; Rayar, M. ^[5] ; Balakirouchenane, D. ^[6] ; Debord, J. ^[7] ; Jezequel, C. ; Camus, C. ; Roussel, M. ; Boudjema, K. ; Verdier, M. C. ; Bellissant, E. ; Lemaitre, F.

作者单位： Rennes Univ Hosp, Haematol Lab, Rennes, France ^[1] Cochin Hosp, AP HP, Pharmacokinet & Pharmacochem Dept, Paris, France ^[2] Rennes Univ Hosp, Dept Med Intens Care Unit, Rennes, France ^[3] Univ Limoges, CHU Limoges, INSERM, Dept Pharmacol & Toxicol,UMR 1248, Limoges, France ^[4] Rennes Univ Hosp, Hepatobiliary & Digest Surg Unit, Rennes, France ^[5] Rennes Univ Hosp, Dept Mol Genet & Genom, Rennes, France ^[6] Rennes Univ Hosp, INSERM, Dept Pharmacol, CIC P 1414 Clin Invest Ctr, Rennes, France ^[7]

关键词 Tacrolimus pharmacogenetics pharmacodynamics modeling liver transplantation

发布时间 2021-09-04

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