AhR, ARNT, and CYP1A1 mRNA quantitation in cultured human embryonic palates exposed to TCDD and comparison with mouse palate in vivo and in culture.
第一作者:
B D,Abbott
第一单位:
Reproductive Toxicology Division, National Health Effects and Environmental Research Laboratory, Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA.
作者:
主题词
动物(Animals);芳香烃受体核转位子(Aryl Hydrocarbon Receptor Nuclear Translocator);碱基序列(Base Sequence);细胞色素P450 CYP1A1(Cytochrome P-450 CYP1A1);DNA结合蛋白质类(DNA-Binding Proteins);剂量效应关系, 药物(Dose-Response Relationship, Drug);环境污染物(Environmental Pollutants);人类(Humans);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);分子序列数据(Molecular Sequence Data);器官培养技术(Organ Culture Techniques);腭(Palate);RNA, 信使(RNA, Messenger);受体, 芳基烃(Receptors, Aryl Hydrocarbon);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);致畸剂(Teratogens);时间因素(Time Factors);转录因子(Transcription Factors)
DOI
10.1093/toxsci/47.1.62
PMID
10048154
发布时间
2019-05-13
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Toxicological sciences
62-75页
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