Targeted remodeling of human beta-globin promoter chromatin structure produces increased expression and decreased silencing.
第一作者:
N,Iler
第一单位:
Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.
作者:
医学主题词
染色质(Chromatin);DNA(DNA);DNA结合蛋白质类(DNA-Binding Proteins);红细胞(Erythrocytes);红系细胞特异性DNA结合因子类(Erythroid-Specific DNA-Binding Factors);GATA1转录因子(GATA1 Transcription Factor);基因表达调控(Gene Expression Regulation);珠蛋白类(Globins);人类(Humans);NF-E2转录因子(NF-E2 Transcription Factor);NF-E2转录因子, p45亚基(NF-E2 Transcription Factor, p45 Subunit);启动区, 遗传(Promoter Regions, Genetic);转录因子(Transcription Factors);转录, 遗传(Transcription, Genetic)
DOI
10.1006/bcmd.1999.0226
PMID
10349513
发布时间
2008-11-21
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