Loss of differentiation of 4NQO-induced rat malignant oral keratinocytes correlates with metastatic dissemination and is associated with a reduced cellular response to TGF-beta1 and an altered receptor profile.
第一作者:
M,Davies
第一单位:
Department of Oral and Dental Science, University of Bristol, UK.
作者:
医学主题词
4-硝基喹啉-1-氧化物(4-Nitroquinoline-1-oxide);动物(Animals);癌(Carcinoma);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞分化(Cell Differentiation);细胞移植(Cell Transplantation);克隆细胞(Clone Cells);角蛋白细胞(Keratinocytes);肺肿瘤(Lung Neoplasms);淋巴转移(Lymphatic Metastasis);男(雄)性(Male);小鼠(Mice);小鼠, 裸(Mice, Nude);口腔肿瘤(Mouth Neoplasms);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);受体, 转化生长因子β(Receptors, Transforming Growth Factor beta);转化生长因子β(Transforming Growth Factor beta);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1111/j.1600-0714.1999.tb02110.x
PMID
10535362
发布时间
2019-09-15
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