Stromelysin (MMP-3) synthesis is up-regulated in estrogen-deficient mouse osteoblasts in vivo and in vitro.
第一作者:
J J,Breckon
第一单位:
Bone Biology Unit, Department of Orthodontics, GKT School of Medicine and Dentistry, Guy's Hospital, London, United Kingdom.
作者:
医学主题词
动物(Animals);印迹法, RNA(Blotting, Northern);细胞, 培养的(Cells, Cultured);胶原酶类(Collagenases);雌激素类(Estrogens);股骨头(Femur Head);腰椎(Lumbar Vertebrae);基质金属蛋白酶2(Matrix Metalloproteinase 2);基质金属蛋白酶3(Matrix Metalloproteinase 3);基质金属蛋白酶9(Matrix Metalloproteinase 9);小鼠(Mice);成骨细胞(Osteoblasts);卵巢切除术(Ovariectomy);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);金属蛋白酶1组织抑制剂(Tissue Inhibitor of Metalloproteinase-1);金属蛋白酶2组织抑制剂(Tissue Inhibitor of Metalloproteinase-2);增量调节(Up-Regulation)
DOI
10.1359/jbmr.1999.14.11.1880
PMID
10571688
发布时间
2006-11-15
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