Insights into the structure and substrate interactions of the P-glycoprotein multidrug transporter from spectroscopic studies.
第一作者:
F J,Sharom
第一单位:
Guelph-Waterloo Centre for Graduate Work in Chemistry and Biochemistry, Department of Chemistry and Biochemistry, University of Guelph, Guelph, Ont., Canada. sharom@chembio.uoguelph.ca
作者:
医学主题词
腺苷三磷酸(Adenosine Triphosphate);苯胺基萘磺酸类(Anilino Naphthalenesulfonates);结合部位(Binding Sites);载体蛋白质类(Carrier Proteins);细胞膜(Cell Membrane);圆二色性(Circular Dichroism);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);脂双层(Lipid Bilayers);药用制剂(Pharmaceutical Preparations);蛋白质构象(Protein Conformation);溶解度(Solubility);光谱法, 荧光(Spectrometry, Fluorescence);谱学, 傅里叶变换红外(Spectroscopy, Fourier Transform Infrared);底物特异性(Substrate Specificity)
DOI
10.1016/s0005-2736(99)00166-2
PMID
10581365
发布时间
2022-04-08
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