Positive regulation of c-Jun N-terminal kinase and TNF-alpha production but not histamine release by SHP-1 in RBL-2H3 mast cells.
第一作者:
Z H,Xie
第一单位:
Receptors and Signal Transduction Section, OIIB, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA. zxie@dir.nidr.nih.gov
作者:
主题词
动物(Animals);抗原(Antigens);减量调节(Down-Regulation);酶前体(Enzyme Precursors);组胺释放(Histamine Release);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);JNK丝裂原活化蛋白激酶类(JNK Mitogen-Activated Protein Kinases);MAP激酶信号系统(MAP Kinase Signaling System);肥大细胞(Mast Cells);丝裂原激活蛋白激酶类(Mitogen-Activated Protein Kinases);分子量(Molecular Weight);磷蛋白类(Phosphoproteins);磷酰化(Phosphorylation);蛋白质酪氨酸磷酸酶, 非受体11型(Protein Tyrosine Phosphatase, Non-Receptor Type 11);蛋白酪氨酸磷酸酶, 非受体6型(Protein Tyrosine Phosphatase, Non-Receptor Type 6);蛋白质酪氨酸磷酸酶类(Protein Tyrosine Phosphatases);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases);大鼠(Rats);受体, IgE(Receptors, IgE);含SH2域蛋白质酪氨酸磷酸酶类(SH2 Domain-Containing Protein Tyrosine Phosphatases);底物特异性(Substrate Specificity);转染(Transfection);肿瘤细胞, 培养的(Tumor Cells, Cultured);肿瘤坏死因子α(Tumor Necrosis Factor-alpha);酪氨酸(Tyrosine);src同源域(src Homology Domains)
DOI
10.4049/jimmunol.164.3.1521
PMID
10640770
发布时间
2019-05-15
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