Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment.
第一作者:
T,Wekerle
第一单位:
BMT Section, Transplantation Biology Research Center, Massachusetts General Hospital/Harvard Medical School, MGH East, Bldg. 149-5102, 13th Street, Boston, Massachusetts 02129, USA.
作者:
医学主题词
动物(Animals);抗原, CD(Antigens, CD);抗原, 分化(Antigens, Differentiation);骨髓移植(Bone Marrow Transplantation);CD40配体(CD40 Ligand);女(雌)性(Female);免疫耐受(Immune Tolerance);免疫轭合物(Immunoconjugates);膜糖蛋白类(Membrane Glycoproteins);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);受体, 抗原, T细胞, α-β(Receptors, Antigen, T-Cell, alpha-beta);移植嵌合体(Transplantation Chimera);移植免疫学(Transplantation Immunology);移植, 同种(Transplantation, Homologous)
DOI
10.1038/74731
PMID
10742157
发布时间
2022-03-11
基金项目
R01HL49915/HL/NHLBI NIH HHS/United States
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Nature medicine
464-9页
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