换一批3Beta-hydroxy-6-aza-cholestane and related analogues as phosphatidylinositol specific phospholipase C (PI-PLC) inhibitors with antitumor activity.
第一作者：
W,Xie
第一单位：
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta 30332, USA.
作者：
医学主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);氮杂化合物(Aza Compounds);胆甾烷醇类(Cholestanols);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);酶抑制剂(Enzyme Inhibitors);人类(Humans);小鼠(Mice);小鼠, SCID(Mice, SCID);肿瘤移植(Neoplasm Transplantation);磷脂酰肌醇二酰甘油裂合酶(Phosphatidylinositol Diacylglycerol-Lyase);磷脂酰肌醇磷脂酶C(Phosphoinositide Phospholipase C);光谱分析(Spectrum Analysis);肿瘤细胞, 培养的(Tumor Cells, Cultured);C型磷脂酶类(Type C Phospholipases)
DOI
10.1016/s0968-0896(00)00014-6
PMID
10819158
发布时间
2019-08-31
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