Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria.
第一作者:
D,Genini
第一单位:
Department of Medicine and The Sam and Rose Stein Institute for Research on Aging, Whittier Diabetes Program, University of California, San Diego, La Jolla, CA, USA.
作者:
医学主题词
腺嘌呤核苷酸类(Adenine Nucleotides);腺苷三磷酸(Adenosine Triphosphate);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);阿糖核苷类(Arabinonucleosides);B-淋巴细胞(B-Lymphocytes);细胞存活(Cell Survival);克利屈滨(Cladribine);彗星试验(Comet Assay);DNA损伤(DNA Damage);DNA, 线粒体(DNA, Mitochondrial);脱氧腺苷类(Deoxyadenosines);人类(Humans);免疫组织化学(Immunohistochemistry);白血病, 淋巴细胞, 慢性, B细胞(Leukemia, Lymphocytic, Chronic, B-Cell);膜电位(Membrane Potentials);微量注射(Microinjections);线粒体(Mitochondria);时间因素(Time Factors);肿瘤细胞, 培养的(Tumor Cells, Cultured);阿糖腺苷(Vidarabine)
PMID
11071652
发布时间
2021-02-16
- 浏览6
Blood
3537-43页
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