X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center.
第一作者:
T,Hishiki
第一单位:
Department of Biochemistry, School of Medicine, Keio University, Shinano-machi, Shinjuku-ku, Tokyo 160-8582, Japan.
作者:
医学主题词
结合部位(Binding Sites);樟脑(Camphor);樟脑5-单加氧酶(Camphor 5-Monooxygenase);催化作用(Catalysis);结晶学, X线(Crystallography, X-Ray);电子转运(Electron Transport);异亮氨酸(Isoleucine);模型, 分子(Models, Molecular);诱变, 定点(Mutagenesis, Site-Directed);氧(Oxygen);蛋白质构象(Protein Conformation);分光光度法, 紫外线(Spectrophotometry, Ultraviolet);苏氨酸(Threonine);水(Water)
DOI
10.1093/oxfordjournals.jbchem.a022848
PMID
11098139
发布时间
2019-05-13
- 浏览10
Journal of biochemistry
965-74页
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