换一批Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction.
第一作者：
S,Negoro
第一单位：
Department of Molecular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
作者：
医学主题词
动物(Animals);动物, 新生(Animals, Newborn);抗原, CD(Antigens, CD);细胞凋亡(Apoptosis);载体蛋白质类(Carrier Proteins);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞存活(Cell Survival);细胞, 培养的(Cells, Cultured);细胞因子受体gp130(Cytokine Receptor gp130);DNA碎片裂(DNA Fragmentation);剂量效应关系, 药物(Dose-Response Relationship, Drug);多柔比星(Doxorubicin);酶激活(Enzyme Activation);酶类(Enzymes);生长抑制物(Growth Inhibitors);心室(Heart Ventricles);原位缺口末端标记(In Situ Nick-End Labeling);白细胞介素6(Interleukin-6);白血病抑制因子(Leukemia Inhibitory Factor);白血病抑制因子受体α亚单位(Leukemia Inhibitory Factor Receptor alpha Subunit);淋巴因子(Lymphokines);膜糖蛋白类(Membrane Glycoproteins);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);磷酰化(Phosphorylation);蛋白质结合(Protein Binding);原癌基因蛋白质类(Proto-Oncogene Proteins);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);受体, 细胞因子(Receptors, Cytokine);受体, OSM-LIF(Receptors, OSM-LIF);bcl相关死亡蛋白质(bcl-Associated Death Protein);bcl-X蛋白质(bcl-X Protein)
DOI
10.1161/01.cir.103.4.555
PMID
11157722
发布时间
2021-12-03
- 浏览24
Circulation
555-61页
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