换一批A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain.
第一作者：
C,Gaiddon
第一单位：
Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
作者：
医学主题词
抗体, 单克隆(Antibodies, Monoclonal);细胞, 培养的(Cells, Cultured);DNA结合蛋白质类(DNA-Binding Proteins);减量调节(Down-Regulation);基因, 报告(Genes, Reporter);基因, 肿瘤抑制(Genes, Tumor Suppressor);基因, p53(Genes, p53);遗传载体(Genetic Vectors);HSC70热休克蛋白质类(HSC70 Heat-Shock Proteins);HSP70热休克蛋白质类(HSP70 Heat-Shock Proteins);人类(Humans);萤光素酶类(Luciferases);膜蛋白质类(Membrane Proteins);突变(Mutation);肿瘤(Neoplasms);核蛋白质类(Nuclear Proteins);磷蛋白类(Phosphoproteins);沉淀素试验(Precipitin Tests);蛋白质结合(Protein Binding);蛋白质亚型(Protein Isoforms);蛋白质结构, 三级(Protein Structure, Tertiary);反式激活因子类(Trans-Activators);转录因子(Transcription Factors);转录激活(Transcriptional Activation);转染(Transfection);肿瘤细胞, 培养的(Tumor Cells, Cultured);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)
DOI
10.1128/MCB.21.5.1874-1887.2001
PMID
11238924
发布时间
2022-03-21
基金项目
R01 CA077742/CA/NCI NIH HHS/United States
CA77742/CA/NCI NIH HHS/United States
- 浏览61
Molecular and cellular biology
1874-87页
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