Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: protein kinase A-dependent mechanism.
第一作者:
S,Cho
第一单位:
Department of Neurology and Neuroscience, Weill Medical College of Cornell University at Burke Medical Research Institute, 785 Mamaroneck Ave., White Plains, NY 10605, USA. scho@burke.org
作者:
主题词
动物(Animals);细胞系, 转化(Cell Line, Transformed);环AMP(Cyclic AMP);cAMP反应元件结合蛋白质(Cyclic AMP Response Element-Binding Protein);环AMP依赖性蛋白激酶Ⅱ型(Cyclic AMP-Dependent Protein Kinase Type II);环AMP依赖性蛋白激酶类(Cyclic AMP-Dependent Protein Kinases);多巴胺(Dopamine);GTP环化水解酶(GTP Cyclohydrolase);基因表达调控, 酶学(Gene Expression Regulation, Enzymologic);白细胞介素1(Interleukin-1);小神经胶质细胞(Microglia);NF-κB(NF-kappa B);神经保护药(Neuroprotective Agents);一氧化氮合酶(Nitric Oxide Synthase);一氧化氮合酶Ⅱ型(Nitric Oxide Synthase Type II);RNA, 信使(RNA, Messenger);转录, 遗传(Transcription, Genetic);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1002/1098-1136(20010315)33:4<324::aid-glia1031>3.0.co;2-m
PMID
11246231
发布时间
2019-11-04
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