Hypoxia-inducible factor-1 activation and cyclo-oxygenase-2 induction are early reperfusion-independent inflammatory events in hemorrhagic shock.
第一作者:
C,Hierholzer
第一单位:
Department of Surgery, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
作者:
主题词
动物(Animals);环氧化酶2(Cyclooxygenase 2);DNA结合蛋白质类(DNA-Binding Proteins);酶诱导(Enzyme Induction);基因表达(Gene Expression);缺氧诱导因子1(Hypoxia-Inducible Factor 1);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);同工酶类(Isoenzymes);肺(Lung);男(雄)性(Male);核蛋白质类(Nuclear Proteins);前列腺素内过氧化物合酶类(Prostaglandin-Endoperoxide Synthases);RNA, 信使(RNA, Messenger);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);再灌注损伤(Reperfusion Injury);休克, 出血性(Shock, Hemorrhagic);全身炎症反应综合征(Systemic Inflammatory Response Syndrome);转录因子(Transcription Factors);增量调节(Up-Regulation)
DOI
10.1007/s004020000211
PMID
11317684
发布时间
2019-09-21
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