Suppression of colorectal cancer growth using an adenovirus vector expressing an antisense K-ras RNA.
第一作者:
M,Nakano
第一单位:
Genetics Division, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
作者:
医学主题词
腺病毒科(Adenoviridae);动物(Animals);印迹法, RNA(Blotting, Northern);印迹法, 蛋白质(Blotting, Western);细胞系(Cell Line);结直肠肿瘤(Colorectal Neoplasms);DNA, 互补(DNA, Complementary);剂量效应关系, 药物(Dose-Response Relationship, Drug);减量调节(Down-Regulation);基因, ras(Genes, ras);肝细胞(Hepatocytes);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, SCID(Mice, SCID);模型, 遗传学(Models, Genetic);寡核苷酸类, 反义(Oligonucleotides, Antisense);点突变(Point Mutation);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));RNA(RNA);时间因素(Time Factors);转导, 遗传(Transduction, Genetic);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1006/mthe.2001.0302
PMID
11319909
发布时间
2006-11-15
- 浏览14
Molecular therapy
491-9页
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