Characterization of two evolutionarily conserved, alternatively spliced nuclear phosphoproteins, NFAR-1 and -2, that function in mRNA processing and interact with the double-stranded RNA-dependent protein kinase, PKR.
第一作者:
L R,Saunders
第一单位:
Department of Microbiology and Immunology and Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, Florida 33136, USA.
作者:
医学主题词
选择性剪接(Alternative Splicing);氨基酸序列(Amino Acid Sequence);动物(Animals);碱基序列(Base Sequence);COS细胞(COS Cells);细胞核(Cell Nucleus);DNA引物(DNA Primers);DNA, 互补(DNA, Complementary);进化, 分子(Evolution, Molecular);分子序列数据(Molecular Sequence Data);核因子90蛋白质类(Nuclear Factor 90 Proteins);磷蛋白类(Phosphoproteins);沉淀素试验(Precipitin Tests);蛋白质亚型(Protein Isoforms);RNA加工, 转录后(RNA Processing, Post-Transcriptional);RNA, 信使(RNA, Messenger);RNA结合蛋白质类(RNA-Binding Proteins);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);序列同源性, 氨基酸(Sequence Homology, Amino Acid);底物特异性(Substrate Specificity);eIF-2激酶(eIF-2 Kinase)
DOI
10.1074/jbc.M104207200
PMID
11438536
发布时间
2021-02-09
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