Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase.
第一作者:
A,Mudher
第一单位:
Departments of Neuroscience and Psychiatry, Institute of Psychiatry, King's College London, London SE5 8AF, United Kingdom.
作者:
医学主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);阿尔茨海默病(Alzheimer Disease);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);钙-钙调素依赖性蛋白激酶类(Calcium-Calmodulin-Dependent Protein Kinases);细胞系(Cell Line);内肽酶类(Endopeptidases);基因表达(Gene Expression);糖原合成酶激酶3(Glycogen Synthase Kinase 3);糖原合成酶激酶类(Glycogen Synthase Kinases);人类(Humans);JNK丝裂原活化蛋白激酶类(JNK Mitogen-Activated Protein Kinases);肾(Kidney);丝裂原激活蛋白激酶类(Mitogen-Activated Protein Kinases);突变(Mutation);磷蛋白类(Phosphoproteins);磷酰化(Phosphorylation);蛋白激酶C(Protein Kinase C);蛋白质类(Proteins);原癌基因蛋白质类(Proto-Oncogene Proteins);重组融合蛋白质类(Recombinant Fusion Proteins);信号传导(Signal Transduction);转染(Transfection);Wnt蛋白质类(Wnt Proteins);Wnt1蛋白质(Wnt1 Protein);斑马鱼蛋白质类(Zebrafish Proteins);tau蛋白质类(tau Proteins)
PMID
11438574
发布时间
2026-03-12
- 浏览10
The Journal of neuroscience
4987-95页
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