Human wild presenilin-1 mimics the effect of the mutant presenilin-1 on the processing of Alzheimer's amyloid precursor protein in PC12D cells.
第一作者:
F,Kametani
第一单位:
Department of Molecular Biology, Tokyo Institute of Psychiatry, 2-1-8 Kamikitazawa, Setagayaku, 156-8585, Tokyo, Japan. kametani@prit.go.jp
作者:
主题词
阿尔茨海默病(Alzheimer Disease);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);动物(Animals);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);内肽酶类(Endopeptidases);人类(Humans);细胞内膜(Intracellular Membranes);膜蛋白质类(Membrane Proteins);突变(Mutation);PC12细胞(PC12 Cells);早老素1(Presenilin-1);蛋白质加工, 转译后(Protein Processing, Post-Translational);大鼠(Rats)
DOI
10.1016/s0022-510x(01)00543-3
PMID
11489281
发布时间
2019-07-24
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