The link between heparan sulfate and hereditary bone disease: finding a function for the EXT family of putative tumor suppressor proteins.
第一作者:
G,Duncan
第一单位:
Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
作者:
医学主题词
乙酰葡萄糖胺(Acetylglucosamine);成年人(Adult);动物(Animals);生物聚合物(Biopolymers);骨发育(Bone Development);骨肿瘤(Bone Neoplasms);CHO细胞(CHO Cells);软骨(Cartilage);儿童(Child);仓鼠亚科(Cricetinae);DNA突变分析(DNA Mutational Analysis);进化, 分子(Evolution, Molecular);外生骨疣, 多发性遗传性(Exostoses, Multiple Hereditary);基因, 显性(Genes, Dominant);基因, 致死(Genes, Lethal);基因, 肿瘤抑制(Genes, Tumor Suppressor);遗传互补测验(Genetic Complementation Test);疾病遗传易感性(Genetic Predisposition to Disease);葡糖醛酸(Glucuronic Acid);糖基化(Glycosylation);硫酸乙酰肝素(Heparitin Sulfate);人类(Humans);无脊椎动物(Invertebrates);大分子物质(Macromolecular Substances);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);模型, 生物学(Models, Biological);N-乙酰氨基葡糖转移酶类(N-Acetylglucosaminyltransferases);甲状旁腺激素相关蛋白质(Parathyroid Hormone-Related Protein);蛋白质类(Proteins);受体, 甲状旁腺激素, 1型(Receptor, Parathyroid Hormone, Type 1);受体, 甲状旁腺激素(Receptors, Parathyroid Hormone);危险(Risk);构效关系(Structure-Activity Relationship);脊椎动物(Vertebrates)
DOI
10.1172/JCI13737
PMID
11518722
发布时间
2025-01-03
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