Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo.
第一作者:
P N,Reynolds
第一单位:
Division of Human Gene Therapy, Departments of Medicine, Surgery and Pathology, and Gene Therapy Center, University of Alabama at Birmingham, USA. Paul.Reynolds@ccc.uab.edu
作者:
主题词
腺病毒科(Adenoviridae);动物(Animals);细胞系(Cell Line);内皮生长因子类(Endothelial Growth Factors);内皮(Endothelium);内皮, 血管(Endothelium, Vascular);基因转移技术(Gene Transfer Techniques);遗传载体(Genetic Vectors);免疫组织化学(Immunohistochemistry);肝(Liver);萤光素酶类(Luciferases);肺(Lung);淋巴因子(Lymphokines);男(雄)性(Male);小鼠(Mice);肽基二肽酶A(Peptidyl-Dipeptidase A);启动区, 遗传(Promoter Regions, Genetic);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);组织分布(Tissue Distribution);转录, 遗传(Transcription, Genetic);转导, 遗传(Transduction, Genetic);转基因(Transgenes);血管内皮生长因子A(Vascular Endothelial Growth Factor A);血管内皮生长因子类(Vascular Endothelial Growth Factors)
DOI
10.1038/nbt0901-838
PMID
11533642
发布时间
2012-11-15
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Nature biotechnology
838-42页
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