Methylation of promoter proximal-transcribed sequences of an embryonic globin gene inhibits transcription in primary erythroid cells and promotes formation of a cell type-specific methyl cytosine binding complex.
第一作者:
Rakesh,Singal
第一单位:
Massey Cancer Center and Departments of Internal Medicine and Human Genetics, Virginia Commonwealth University, Richmond, Virginia 23298-0037, USA.
作者:
医学主题词
动物(Animals);碱基序列(Base Sequence);细胞, 培养的(Cells, Cultured);鸡胚(Chick Embryo);胞嘧啶(Cytosine);DNA甲基化(DNA Methylation);酶抑制剂(Enzyme Inhibitors);红细胞(Erythrocytes);珠蛋白类(Globins);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);羟肟酸类(Hydroxamic Acids);分子序列数据(Molecular Sequence Data);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);转录, 遗传(Transcription, Genetic);转染(Transfection)
DOI
10.1074/jbc.M105580200
PMID
11684679
发布时间
2022-03-17
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