Cyclosporine A inhibits the adaptive responses to hypertonicity: a potential mechanism of nephrotoxicity.
第一作者:
David,Sheikh-Hamad
第一单位:
*Renal Section, Department of Medicine, Department of Pathology, and the Harry B. and Aileen Gordon Diabetes Research Laboratory, Molecular Diabetes and Metabolism Section, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
作者:
主题词
适应, 生理学(Adaptation, Physiological);动物(Animals);细胞凋亡(Apoptosis);生物转运(Biological Transport);细胞系(Cell Line);细胞核(Cell Nucleus);环孢菌素(Cyclosporine);DNA结合蛋白质类(DNA-Binding Proteins);狗(Dogs);基因表达(Gene Expression);基因表达调控(Gene Expression Regulation);热休克蛋白质类(Heat-Shock Proteins);人类(Humans);高渗溶液(Hypertonic Solutions);免疫抑制剂(Immunosuppressive Agents);肾疾病(Kidney Diseases);肾髓质(Kidney Medulla);男(雄)性(Male);丝裂原活化蛋白激酶8(Mitogen-Activated Protein Kinase 8);丝裂原激活蛋白激酶类(Mitogen-Activated Protein Kinases);NFATC转录因子类(NFATC Transcription Factors);渗透压(Osmotic Pressure);RNA, 信使(RNA, Messenger);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);反应元件(Response Elements);转录因子(Transcription Factors);水电解质平衡(Water-Electrolyte Balance)
DOI
10.1681/ASN.V12122732
PMID
11729242
发布时间
2021-05-13
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