PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies.
第一作者:
S,Sachdev
第一单位:
Gene Center and Institute of Biochemistry, University of Munich, 81377 Munich, Germany.
作者:
医学主题词
动物(Animals);载体蛋白质类(Carrier Proteins);细胞系(Cell Line);染色体(Chromosomes);DNA(DNA);DNA结合蛋白质类(DNA-Binding Proteins);电泳迁移位移试验(Electrophoretic Mobility Shift Assay);荧光抗体技术(Fluorescent Antibody Technique);基因表达调控(Gene Expression Regulation);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);连接酶类(Ligases);淋巴样增强子结合因子1(Lymphoid Enhancer-Binding Factor 1);小鼠(Mice);显微镜检查, 共焦(Microscopy, Confocal);诱变, 定点(Mutagenesis, Site-Directed);核基质(Nuclear Matrix);细胞器(Organelles);蛋白质结合(Protein Binding);活化STAT的蛋白抑制物(Protein Inhibitors of Activated STAT);蛋白质转运(Protein Transport);信号传导(Signal Transduction);小泛素相关修饰蛋白质类(Small Ubiquitin-Related Modifier Proteins);转录因子(Transcription Factors);转录, 遗传(Transcription, Genetic);双杂交系统技术(Two-Hybrid System Techniques);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)
DOI
10.1101/gad.944801
PMID
11731474
发布时间
2024-11-22
- 浏览43
Genes & development
3088-103页
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