换一批ATM gene inactivation in mantle cell lymphoma mainly occurs by truncating mutations and missense mutations involving the phosphatidylinositol-3 kinase domain and is associated with increasing numbers of chromosomal imbalances.
第一作者：
Emma,Camacho
第一单位：
Department of Anatomic Pathology, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Spain.
作者：
医学主题词
等位基因(Alleles);印迹法, 蛋白质(Blotting, Western);细胞周期蛋白质类(Cell Cycle Proteins);染色体畸变(Chromosome Aberrations);染色体, 人, 11对(Chromosomes, Human, Pair 11);DNA突变分析(DNA Mutational Analysis);DNA结合蛋白质类(DNA-Binding Proteins);基因缺失(Gene Deletion);基因表达(Gene Expression);人类(Humans);淋巴瘤, 膜细胞(Lymphoma, Mantle-Cell);突变(Mutation);突变, 误义(Mutation, Missense);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);多态现象, 遗传(Polymorphism, Genetic);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)
DOI
10.1182/blood.v99.1.238
PMID
11756177
发布时间
2021-12-03
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Blood
238-44页
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