Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor.
第一作者:
Borlan,Pan
第一单位:
Department of Protein Engineering, Genentech Inc., South San Francisco, CA 94080, USA.
作者:
主题词
丙氨酸(Alanine);氨基酸序列(Amino Acid Sequence);细菌噬菌体(Bacteriophages);结合部位(Binding Sites);结晶学, X线(Crystallography, X-Ray);二聚作用(Dimerization);二硫化物类(Disulfides);内皮生长因子类(Endothelial Growth Factors);人类(Humans);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);淋巴因子(Lymphokines);模型, 分子(Models, Molecular);分子序列数据(Molecular Sequence Data);突变(Mutation);核磁共振, 生物分子(Nuclear Magnetic Resonance, Biomolecular);肽类(Peptides);蛋白质结构, 四级(Protein Structure, Quaternary);蛋白质结构, 二级(Protein Structure, Secondary);蛋白质结构, 三级(Protein Structure, Tertiary);原癌基因蛋白质类(Proto-Oncogene Proteins);受体蛋白质酪氨酸激酶类(Receptor Protein-Tyrosine Kinases);受体, 生长因子(Receptors, Growth Factor);受体, 血管内皮生长因子(Receptors, Vascular Endothelial Growth Factor);溶液(Solutions);血管内皮生长因子A(Vascular Endothelial Growth Factor A);血管内皮生长因子受体1(Vascular Endothelial Growth Factor Receptor-1);血管内皮生长因子类(Vascular Endothelial Growth Factors)
DOI
10.1006/jmbi.2001.5370
PMID
11866530
发布时间
2013-11-21
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