Reduced functional capacity of CD8+ T cells expanded by post-exposure vaccination of gamma-herpesvirus-infected CD4-deficient mice.
作者:
主题词
投药, 鼻内(Administration, Intranasal);动物(Animals);抗原, 细菌(Antigens, Bacterial);细菌蛋白质类(Bacterial Proteins);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞毒性, 免疫(Cytotoxicity, Immunologic);减量调节(Down-Regulation);女(雌)性(Female);丙型疱疹病毒亚科(Gammaherpesvirinae);H-2抗原(H-2 Antigens);疱疹病毒科感染(Herpesviridae Infections);疱疹病毒疫苗(Herpesvirus Vaccines);组织相容性抗原Ⅱ类(Histocompatibility Antigens Class II);免疫表型分型(Immunophenotyping);干扰素γ(Interferon-gamma);淋巴细胞活化(Lymphocyte Activation);淋巴细胞计数(Lymphocyte Count);淋巴细胞减少(Lymphopenia);膜蛋白质类(Membrane Proteins);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);T淋巴细胞, 细胞毒性(T-Lymphocytes, Cytotoxic);肿瘤坏死因子α(Tumor Necrosis Factor-alpha);肿瘤病毒感染(Tumor Virus Infections);疫苗, 合成(Vaccines, Synthetic);痘苗病毒(Vaccinia virus)
DOI
10.4049/jimmunol.168.7.3477
PMID
11907108
发布时间
2019-05-15
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