Treatment of murine breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor decreases the level of plasminogen activator transcripts, inhibits cell growth in vitro, and reduces tumorigenesis in vivo.
第一作者:
C L,Chernicky
第一单位:
Department of Reproductive Biology, Case Western Reserve University School of Medicine, Cleveland, OH 44106-4943, USA. cheryl.chernicky@uhhs.com
作者:
医学主题词
动物(Animals);乳腺肿瘤(Breast Neoplasms);癌(Carcinoma);细胞分裂(Cell Division);女(雌)性(Female);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);模型, 动物(Models, Animal);肿瘤移植(Neoplasm Transplantation);RNA, 反义(RNA, Antisense);受体, IGF1型(Receptor, IGF Type 1);组织型纤溶酶原激活物(Tissue Plasminogen Activator);转染(Transfection);肿瘤细胞, 培养的(Tumor Cells, Cultured);尿激酶型纤溶酶原激活物(Urokinase-Type Plasminogen Activator)
DOI
10.1136/mp.55.2.102
PMID
11950959
发布时间
2019-05-03
- 浏览14
Molecular pathology
102-9页
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