Tenofovir diphosphate is a poor substrate and a weak inhibitor of rat DNA polymerases alpha, delta, and epsilon*.
第一作者:
Gabriel,Birkus
第一单位:
Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic. Gabriel_Birkus@gilead.com
作者:
医学主题词
腺嘌呤(Adenine);动物(Animals);抗HIV药(Anti-HIV Agents);DNA聚合酶Ⅰ(DNA Polymerase I);DNA聚合酶Ⅱ(DNA Polymerase II);DNA聚合酶Ⅲ(DNA Polymerase III);指导DNA的DNA聚合酶(DNA-Directed DNA Polymerase);核酸合成抑制剂(Nucleic Acid Synthesis Inhibitors);有机磷化合物(Organophosphorus Compounds);大鼠(Rats);逆转录酶抑制剂(Reverse Transcriptase Inhibitors)
DOI
10.1128/AAC.46.5.1610-1613.2002
PMID
11959615
发布时间
2021-05-26
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